Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804829 | 0.91 | NPC1 (0.44) | HSP90AA1HSP90AB1NUDT1CYP1A2CYP2C19 | |
| SCHEMBL7796331 | 0.88 | KMT2A (0.43) | HSP90AA1HSP90AB1NUDT1KMT2AMEN1 | |
| SCHEMBL7934010 | 0.88 | KMT2A (0.49) | HSP90AA1HSP90AB1KMT2AMEN1CYP2C19 | |
| SCHEMBL7932060 | 0.87 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL8874243 | 0.86 | RAB9A (0.48) | HSP90AA1HSP90AB1NUDT1CYP1A2CYP2C19 | |
| SCHEMBL8874417 | 0.82 | GABRP (0.32) | HSP90AA1HSP90AB1NUDT1KMT2AMEN1 | |
| SCHEMBL8874050 | 0.82 | NUDT1 (0.44) | HSP90AA1HSP90AB1NUDT1KMT2AMEN1 | |
| SCHEMBL8874141 | 0.82 | NUDT1 (0.51) | HSP90AA1HSP90AB1NUDT1 | |
| SCHEMBL8873474 | 0.82 | CDK1 (0.37) | NUDT1KMT2AMEN1CYP1A2CYP2C19 | |
| SCHEMBL7933970 | 0.82 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1NUDT1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |