Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7935910 | 0.88 | HSP90AA1 (0.35) | KMT2ASMN1; SMN2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL7806796 | 0.85 | KMT2A (0.45) | KMT2ASMN1; SMN2HSP90AA1HSP90AB1NUDT1 | |
| SCHEMBL7934010 | 0.81 | KMT2A (0.49) | KMT2ASMN1; SMN2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL7804843 | 0.81 | — | — | |
| SCHEMBL7932060 | 0.80 | HSP90AA1 (0.50) | KMT2AHSP90AA1HSP90AB1CYP1A2CYP2C19 | |
| SCHEMBL7804829 | 0.80 | NPC1 (0.44) | SMN1; SMN2HSP90AA1HSP90AB1NUDT1CYP1A2 | |
| SCHEMBL8874243 | 0.76 | RAB9A (0.48) | SMN1; SMN2HSP90AA1HSP90AB1NUDT1CYP1A2 | |
| SCHEMBL8874141 | 0.76 | NUDT1 (0.51) | HSP90AA1HSP90AB1NUDT1 | |
| SCHEMBL8874050 | 0.76 | NUDT1 (0.44) | KMT2ASMN1; SMN2HSP90AA1HSP90AB1MEN1 | |
| SCHEMBL8874417 | 0.76 | GABRP (0.32) | KMT2AHSP90AA1HSP90AB1MEN1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | claimed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | claimed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | claimed |
| JP-4211669-A | — | — | None | — | — | JP | disclosed |
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0572429-B1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF AG (DE) | 2001-04-18 | — | — | EP | disclosed |
| US-5591694-A | COMPOUND USED TO CONTROL UNDESIRABLE PLANT GROWTH | BASF AKTIENGESELLSCHAFT (DE) | 1997-01-07 | — | — | US | disclosed |
| EP-0446743-B1 | Herbicidal sulfonylureas, process for their preparation and intermediates | BASF AG (DE) | 1995-08-02 | — | — | EP | disclosed |
| US-5434124-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1995-07-18 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0445644-B1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF AG (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-5276007-A | Herbicidal sulfonylureas | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0572429-A1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF Aktiengesellschaft (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5237063-A | TRIFLUORO- AND CHLORODIFLUOROMETHOXYPYRIMIDINES AND THE PREPARATION THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1993-08-17 | — | — | US | disclosed |
| WO-1993005048-A2 | HERBICIDAL SULPHONYL UREAS, PROCESS AND INTERMEDIATES FOR PRODUCING THE SAME | BASF AKTIENGESELLSCHAFT (DE) | 1993-03-18 | — | — | WO | disclosed |
| WO-1992014715-A1 | SULFONYL UREA DERIVATES, METHOD FOR PREPARING THEM AND USE THEREOF | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-03 | — | — | WO | disclosed |
| JP-H04211669-A | 2-AMINO(FLUOROALKOXY) PYRIMIDINE AND ITS PREPARATION | BASF AG | 1992-08-03 | — | — | JP | disclosed |
| EP-0446743-A2 | Herbicidal sulfonylureas, process for their preparation and intermediates | BASF Aktiengesellschaft (DE) | 1991-09-18 | — | — | EP | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0445644-A1 | Trifluoro- respectively chlorodifluoromethoxy pyrimidines and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |