Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GPR39 | O43194 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874284 | 0.92 | CYP1A2 (0.44) | CHRNA7IDH2KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL8874390 | 0.88 | GPR39 (0.37) | CHRNA7IDH2TDP1GPR39ALDH1A1 | |
| SCHEMBL7937932 | 0.88 | CHRNA7 (0.35) | CHRNA7IDH2TDP1GPR39HPGD | |
| SCHEMBL8874210 | 0.88 | SMN1; SMN2 (0.39) | CHRNA7TDP1GPR39MEN1KMT2A | |
| SCHEMBL7934015 | 0.87 | PGK1 (0.35) | CHRNA7IDH2TDP1GPR39HPGD | |
| SCHEMBL7925318 | 0.87 | HPGD (0.45) | CHRNA7IDH2HPGDMEN1KMT2A | |
| SCHEMBL8873701 | 0.84 | NUDT1 (0.38) | CHRNA7IDH2GPR39MEN1KMT2A | |
| SCHEMBL7934055 | 0.83 | IDH2 (0.34) | CHRNA7IDH2TDP1GPR39HPGD | |
| SCHEMBL8873315 | 0.81 | GPR39 (0.41) | CHRNA7TDP1GPR39HPGDMEN1 | |
| SCHEMBL7805860 | 0.77 | CYP1A2 (0.42) | CHRNA7KMT2ACYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235904-B1 | VALUABLE INTERMEDIATES FOR ORGANIC SYNTHESES, ESPECIALLY FOR PREPARING CROP PROTECTION AGENTS. | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-22 | — | — | US | disclosed |
| EP-0445642-B1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF AG (DE) | 1995-07-12 | — | — | EP | disclosed |
| US-5283332-A | 2-amino(fluoroalkoxy)pyrimidines and the preparation thereof | BASF AKTIENGESELLSCHAFT (DE) | 1994-02-01 | — | — | US | disclosed |
| EP-0445642-A1 | 2-Amino-(fluoralkoxy-pyrimidines) and process for their preparation | BASF Aktiengesellschaft (DE) | 1991-09-11 | — | — | EP | disclosed |