Styrene

Styrene

SCHEMBL7932257

C=C(CCCC)C(=O)OO.C=Cc1ccccc1

nearest known ligand 0.40

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
KDM4E B2RXH2 1/20 0.40
RECQL P46063 1/20 0.40
ALDH1A1 P00352 1/20 0.40
TSHR P16473 1/20 0.40
CES2 O00748 3/20 0.40
CES1 P23141 3/20 0.40
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
EGFR P00533 1/20 0.36
HDAC3 O15379 1/20 0.36
PTGES O14684 1/20 0.35
ALOX5 P09917 1/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL17065130 0.86 LMNA (0.47) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL5270544 0.86 LMNA (0.47) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL258132 0.86 LMNA (0.47) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL18789030 0.86 KDM4E (0.46) MEN1KMT2AKDM4EALDH1A1TSHR
Styrene SCHEMBL2942058 0.84 LMNA (0.44) MEN1KMT2AALDH1A1TSHRCES2
Styrene SCHEMBL28077574 0.83 TDP1 (0.46) MEN1KMT2AALDH1A1CES2CES1
Styrene SCHEMBL987788 0.82 LMNA (0.44) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL3430407 0.82 LMNA (0.44) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL7783115 0.82 LMNA (0.44) MEN1KMT2AKDM4ERECQLALDH1A1
Styrene SCHEMBL1476489 0.82 MEN1 (0.49) MEN1KMT2AKDM4EALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0683727-B1 THERMOPLASTIC OLEFINIC COMPOSITIONS SOLVAY ENGINEERED POLYMERS (US) 2001-05-02 EP disclosed
US-5693710-A PAINT COMPOSITION CONTAINING TWO-COMPONENT POLYURETHANE METALLIC BASE AND SOLID BASE COATS AND BLEND OF POLYOLEFIN AND FIRST AND SECOND RUBBERS HONDA GIKEN KOGYO KABUSHIKI KAISHA (JP) 1997-12-02 US disclosed
US-5498671-A ADHESION FOR COATINGS D & S PLASTIC INTERNATIONAL (US) 1996-03-12 US disclosed