Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7616889 | 0.84 | HTR1A (0.80) | HTR1ASLC6A4 | |
| SCHEMBL7616883 | 0.84 | HTR1A (0.80) | HTR1ASLC6A4 | |
| SCHEMBL7619191 | 0.83 | HTR1A (0.78) | HTR1ASLC6A4 | |
| Robalzotan SCHEMBL4811762 | 0.83 | HTR1A (1.00) | HTR1ASLC6A4 | |
| SCHEMBL7619185 | 0.83 | HTR1A (0.78) | HTR1ASLC6A4 | |
| Robalzotan SCHEMBL115079 | 0.83 | HTR1A (1.00) | HTR1ASLC6A4 | |
| SCHEMBL6820286 | 0.82 | HTR1A (0.98) | HTR1ASLC6A4 | |
| SCHEMBL6820275 | 0.82 | HTR1A (0.98) | HTR1ASLC6A4 | |
| SCHEMBL6309751 | 0.81 | HTR1A (0.46) | HTR1ASLC6A4 | |
| SCHEMBL7936073 | 0.80 | HTR1A (0.45) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184219-B1 | Composition and methods employing it for the treatment of 5-HT-mediated disorders | ASTRA AKTIEBOLAG (SE) | 2001-02-06 | — | — | US | disclosed |