Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 12/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309751 | 0.99 | HTR1A (0.46) | HTR1ASLC6A4RAB9AHPGDALDH1A1 | |
| Cadaverine Tartrate SCHEMBL6245775 | 0.92 | HTR1A (0.41) | HTR1ASLC6A4RAB9AHPGD | |
| SCHEMBL7932463 | 0.80 | HTR1A (0.71) | HTR1ASLC6A4 | |
| SCHEMBL27640871 | 0.73 | HTR1A (0.54) | HTR1ASLC6A4RAB9A | |
| SCHEMBL8718022 | 0.71 | HDAC3 (0.43) | HTR1ASLC6A4HPGD | |
| SCHEMBL8242266 | 0.67 | ACHE (0.38) | HTR1ASLC6A4 | |
| SCHEMBL21189313 | 0.64 | MAOB (0.49) | RAB9AHPGDALDH1A1 | |
| SCHEMBL21189388 | 0.63 | NPC1 (0.44) | RAB9AHPGDALDH1A1 | |
| SCHEMBL7616883 | 0.62 | HTR1A (0.80) | HTR1ASLC6A4 | |
| SCHEMBL7616889 | 0.62 | HTR1A (0.80) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184218-B1 | Composition and methods employing it for the treatment of 5-HT-mediated disorders | ASTRA AKTIEBOLAG (SE) | 2001-02-06 | — | — | US | disclosed |