SCHEMBL7932778

SCHEMBL7932778

CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)O)cc1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR2 P50052 10/20 0.85
AGTR1 P30556 10/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9144123 0.93 AGTR2 (0.83) AGTR2AGTR1
SCHEMBL9399232 0.92 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL9241306 0.91 AGTR2 (0.80) AGTR2AGTR1
SCHEMBL9146433 0.91 AGTR1 (0.86) AGTR2AGTR1
SCHEMBL9373638 0.87 AGTR2 (0.90) AGTR2AGTR1
SCHEMBL9565988 0.87 AGTR1 (0.79) AGTR2AGTR1
SCHEMBL9565979 0.87 AGTR1 (0.79) AGTR2AGTR1
SCHEMBL9399562 0.86 AGTR2 (1.00) AGTR2AGTR1
SCHEMBL9145258 0.86 AGTR1 (0.78) AGTR2AGTR1
SCHEMBL9148318 0.85 AGTR2 (0.86) AGTR2AGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6218414-B1 ADMINISTERING AN EFFECTIVE AMOUNT OF AN ANGIOTENSIN II ANTAGONIST AND A BENZOFURAN DERIVATIVE WITH ANTIARRHYTHMIC ACTIVITY FOR THERAPY OF CARDIOVASCULAR COMPLAINTS SANOFI (FR) 2001-04-17 US disclosed