Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CCL2 | P13500 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1980401 | 0.90 | BRD4 (0.35) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL5695982 | 0.86 | BRD4 (0.37) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL137960 | 0.86 | HTR2A (0.39) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL29424565 | 0.86 | HTR2A (0.39) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL28189655 | 0.84 | BRD4 (0.36) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL820052 | 0.84 | HTR2A (0.38) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL30533388 | 0.84 | HTR2A (0.38) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| SCHEMBL31357303 | 0.84 | HTR2A (0.40) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL7622358 | 0.82 | BRD4 (0.35) | BRD4CCL2HTR6HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL5699505 | 0.82 | BRD4 (0.35) | BRD4CCL2HTR6HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |