SCHEMBL7933144

SCHEMBL7933144

CCOC(=O)c1ccc(Nc2ccc3c(c2)C(=O)c2c(O)ccc(O)c2C3=O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
MAPT P10636 4/20 0.53
THRB P10828 3/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
APAF1 O14727 2/20 0.53
KDM4E B2RXH2 1/20 0.53
MITF O75030 1/20 0.53
NR4A1 P22736 1/20 0.53
HTT P42858 1/20 0.53
SMAD3 P84022 1/20 0.53
HKDC1 Q2TB90 1/20 0.53
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
RAB9A P51151 2/20 0.50
SLC2A1 P11166 1/20 0.50
CA12 O43570 3/20 0.49
CA9 Q16790 3/20 0.49
CA7 P43166 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7927188 0.90 CDC25B (0.58) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL7928395 0.89 HPGD (0.51) HPGDMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL7930654 0.87 STS (0.48) HPGDMAPTSMN1; SMN2RAB9ARECQL
SCHEMBL7930594 0.79 SMN1; SMN2 (0.51) HPGDMEN1KMT2AMAPTSMN1; SMN2
SCHEMBL12124929 0.78 RAB9A (0.69) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL7927180 0.77 MAPT (0.53) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL7928282 0.77 APP (0.56) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL7930873 0.76 MEN1 (0.56) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL8393346 0.76 MAPT (0.62) HPGDMEN1KMT2AMAPTTHRB
SCHEMBL21817032 0.74 MAPT (0.60) HPGDMEN1KMT2AMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661350-B1 Quinizarin compound, method for production thereof, and use therefor NIPPON CATALYTIC CHEM IND (JP) 2001-08-22 EP disclosed
US-5817843-A Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1998-10-06 US disclosed
US-5608091-A SHEETS FOR HEAT EXCHANGING AND OPTICAL RECORDING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 1997-03-04 US disclosed
EP-0661350-A1 Quinizarin compound, method for production thereof, and use therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-07-05 EP disclosed