Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT6 | P42226 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7942137 | 0.90 | STAT6 (0.41) | STAT6CYP51A1CCKBRKDM5A | |
| SCHEMBL1931737 | 0.87 | NPC1 (0.42) | STAT6NPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL7942685 | 0.87 | STAT6 (0.47) | STAT6CYP51A1CCKBRKDM5A | |
| SCHEMBL14980527 | 0.85 | CYP51A1 (0.41) | STAT6CYP51A1CCKBRKDM5A | |
| SCHEMBL14980460 | 0.85 | STAT6 (0.41) | STAT6DGAT1CYP51A1CCKBRIDO1 | |
| SCHEMBL7934126 | 0.85 | STAT6 (0.48) | STAT6CYP51A1CCKBR | |
| SCHEMBL14980442 | 0.84 | STAT6 (0.48) | STAT6CYP51A1CCKBR | |
| SCHEMBL7934440 | 0.84 | STAT6 (0.48) | STAT6CYP51A1CCKBR | |
| SCHEMBL14980528 | 0.84 | STAT6 (0.40) | STAT6CYP51A1CCKBRKDM5A | |
| SCHEMBL7945427 | 0.83 | STAT6 (0.45) | STAT6CYP51A1CCKBRKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011914-A1 | TRPV4 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |