SCHEMBL7933228

SCHEMBL7933228

CC(C)C(=O)O.CC(C)C(=O)O.CC(C)C(=O)O.CC(C)C(O)C(C)(C)CO

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.41
TP53 P04637 1/20 0.36
PTGS1 P23219 1/20 0.35
KCNH2 Q12809 1/20 0.35
OR51E2 Q9H255 1/20 0.32
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP3 P08254 1/20 0.31
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
SLC7A5 Q01650 1/20 0.31
PGD P52209 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43994 1.00 TRPA1 (0.41) TRPA1TP53PTGS1KCNH2OR51E2
SCHEMBL29796591 1.00 TRPA1 (0.41) TRPA1TP53PTGS1KCNH2OR51E2
SCHEMBL56322 1.00 TRPA1 (0.41) TRPA1TP53PTGS1KCNH2OR51E2
Benzene SCHEMBL28271106 0.96 TRPA1 (0.47) TRPA1TP53PTGS1KCNH2OR51E2
Acetic Acid SCHEMBL11315936 0.96 TRPA1 (0.39) TRPA1TP53PTGS1KCNH2OR51E2
1,4-Butanediol SCHEMBL28964157 0.92 PTGS1 (0.42) TRPA1TP53PTGS1KCNH2
Phosphoric Acid SCHEMBL28103751 0.92 TRPA1 (0.37) TRPA1TP53PTGS1KCNH2
Propionic Acid SCHEMBL2795059 0.92 FFAR3 (0.37) TRPA1TP53PTGS1KCNH2
Bicarbonate SCHEMBL4019509 0.91 TRPA1 (0.44) TRPA1TP53PTGS1KCNH2
Adipic Acid SCHEMBL27614593 0.89 LMNA (0.38) OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242388-B1 OIL AND GAS WELLS WITH COUPLING SOLVENTS AND SURFACTANTS EASTMAN CHEMICAL COMPANY 2001-06-05 US disclosed