Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 known ✓ | Q12809 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43994 | 0.92 | TRPA1 (0.41) | TRPA1PTGS1KCNH2TP53 | |
| SCHEMBL56322 | 0.92 | TRPA1 (0.41) | TRPA1PTGS1KCNH2TP53 | |
| SCHEMBL7933228 | 0.92 | TRPA1 (0.41) | TRPA1PTGS1KCNH2TP53 | |
| SCHEMBL29796591 | 0.92 | TRPA1 (0.41) | TRPA1PTGS1KCNH2TP53 | |
| Acetic Acid SCHEMBL11315936 | 0.89 | TRPA1 (0.39) | TRPA1PTGS1KCNH2TP53 | |
| Benzene SCHEMBL28271106 | 0.89 | TRPA1 (0.47) | TRPA1PTGS1KCNH2TP53 | |
| Propionic Acid SCHEMBL2795059 | 0.85 | FFAR3 (0.37) | TRPA1PTGS1KCNH2TP53 | |
| 1,4-Butanediol SCHEMBL28964157 | 0.85 | PTGS1 (0.42) | TRPA1PTGS1KCNH2TP53 | |
| Bicarbonate SCHEMBL4019509 | 0.84 | TRPA1 (0.44) | TRPA1PTGS1KCNH2TP53 | |
| Adipic Acid SCHEMBL27614593 | 0.82 | LMNA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563370-A | The cross-linking coating of polymer based on organoxysilanes sealing end | 瓦克化学股份公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-104114625-B | The compositions of polymer based on organoxysilanes end-blocking | 瓦克化学股份公司 | 2016-10-19 | — | — | CN | disclosed |