Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1823075 | 0.72 | NOS2 (0.39) | NOS2 | |
| SCHEMBL13137663 | 0.71 | CHEK1 (0.42) | — | |
| SCHEMBL817822 | 0.67 | NOS2 (0.33) | NOS2 | |
| SCHEMBL16887409 | 0.62 | PLA2G10 (0.40) | NOS2 | |
| SCHEMBL5567264 | 0.61 | GPR35 (0.38) | — | |
| SCHEMBL21261227 | 0.61 | IGF1R (0.35) | — | |
| SCHEMBL14947904 | 0.60 | PDGFRB (0.31) | — | |
| SCHEMBL18405842 | 0.59 | GPR35 (0.31) | — | |
| SCHEMBL13360489 | 0.58 | KDM4E (0.33) | — | |
| SCHEMBL13671831 | 0.57 | GPR35 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157027-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | Basell Technology Company B.V. (NL) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001047939-A1 | HETEROCYCLIC METALLOCENE COMPOUNDS AND USE THEREOF IN CATALYST SYSTEMS FOR PRODUCING OLEFIN POLYMERS | BASELL TECHNOLOGY COMPANY B.V. (NL) | 2001-07-05 | — | — | WO | disclosed |