Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PGK1 | P00558 | 4/20 | 0.42 |
| ▸ | PGK2 | P07205 | 4/20 | 0.42 |
| ▸ | PNMT | P11086 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | TDO2 | P48775 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11164473 | 0.83 | PTGS1 (0.38) | TSHRALDH1A1HTTSMN1; SMN2TTR | |
| SCHEMBL9506520 | 0.83 | TSHR (0.40) | TSHRPGK1PGK2PNMTTTR | |
| SCHEMBL1538759 | 0.80 | TSHR (0.42) | TSHRPGK1PGK2PNMT | |
| SCHEMBL20893302 | 0.80 | PNMT (0.54) | TSHRPGK1PGK2PNMTALDH1A1 | |
| SCHEMBL10585176 | 0.80 | CYP3A4 (0.43) | TSHRPGK1PGK2IDO1LMNA | |
| SCHEMBL3115675 | 0.80 | HDAC4 (0.42) | TSHRPGK1PGK2PNMTALDH1A1 | |
| SCHEMBL8811394 | 0.80 | PGK1 (0.42) | TSHRPGK1PGK2LMNAALDH1A1 | |
| SCHEMBL18839099 | 0.80 | DAO (0.45) | TSHRPGK1PGK2PNMT | |
| SCHEMBL28018616 | 0.78 | TSHR (0.41) | TSHRPGK1PGK2PNMTALDH1A1 | |
| SCHEMBL631114 | 0.77 | TSHR (0.61) | TSHRPGK1PGK2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563033-B1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON USA INC (US) | 1997-01-02 | — | — | EP | claimed |
| EP-0563033-A4 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RES & TECH (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0563033-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE. | CHEVRON RES & TECH (US) | 1993-10-06 | — | — | EP | claimed |
| WO-1992007820-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-05-14 | — | — | WO | claimed |
| US-4966988-A | CHLORINATION FOLLOWED BY FLUORINATION OF M-XYLENE TO FORM 3-TRIFLUOROMETHYL-BENZYL CHLORIDE; CYANATION | CHEVRON RESEARCH COMPANY (US) | 1990-10-30 | — | — | US | claimed |
| CN-117820169-A | Preparation method of m-trifluoromethyl benzyl cyanide | 上海赫腾精细化工有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-109776255-B | Method for preparing 2, 6-dichlorobenzylidene dichloride by low-temperature photochlorination method | 南京工业大学 | 2021-12-07 | — | — | CN | disclosed |
| CN-1257888-C | Method for synthesizing m-trifluoromethyl benzyl cyanide | SHANGHAI NO 4 REAGENT AND HV C (CN) | 2006-05-31 | — | — | CN | disclosed |
| CN-1660789-A | Method for synthesizing m-trifluoromethyl benzyl cyanide | SHISIHEWEI CHEMICAL CO LTD SHA (CN) | 2005-08-31 | — | — | CN | disclosed |
| US-6174415-B1 | RING CHLORINATION IS GREATLY REDUCED IF UNREACTED AROMATIC COMPOUND IS REMOVED AFTER SOME OF IT HAS BEEN CHLORINATED. | OCCIDENTAL CHEMICAL CORPORATION | 2001-01-16 | — | — | US | disclosed |
| WO-2000071495-A1 | CHLORINATING SIDE CHAINS OF AROMATIC COMPOUNDS | OCCIDENTAL CHEMICAL CORPORATION (US) | 2000-11-30 | — | — | WO | disclosed |
| EP-0563033-B1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON USA INC (US) | 1997-01-02 | — | — | EP | disclosed |
| US-4966988-A | CHLORINATION FOLLOWED BY FLUORINATION OF M-XYLENE TO FORM 3-TRIFLUOROMETHYL-BENZYL CHLORIDE; CYANATION | CHEVRON RESEARCH COMPANY (US) | 1990-10-30 | — | — | US | disclosed |
| EP-0150169-B1 | A PROCESS FOR PREPARING SUBSTITUTED BENZOTRICHLORIDE COMPOUNDS | Monsanto Company (US) | 1987-11-11 | — | — | EP | disclosed |
| US-4593144-A | REACTING SUBSTITUTED BENZAL CHLORIDES WITH PRECHLOROALKANE IN PRESENCE OF BASE AND PHASE TRANSFER CATALYST | MONSANTO COMPANY (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0150169-A2 | A process for preparing substituted benzotrichloride compounds | Monsanto Company (US) | 1985-07-31 | — | — | EP | disclosed |
| US-4399311-A | Process for producing aromatic aldehydes | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1983-08-16 | — | — | US | disclosed |
| US-4328374-A | Process for the production of aromatic dialdehydes | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 1982-05-04 | — | — | US | disclosed |
| US-4048033-A | FROM THE PARTIALLY CHLORINATED METHYLBENZENE AND CHLORINE, ULTRAVIOLET RADIATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1977-09-13 | — | — | US | disclosed |
| US-4029560-A | CHLORINATION OF XYLENE, ULTRAVIOLET RADIATION | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) | 1977-06-14 | — | — | US | disclosed |