SCHEMBL7933489

SCHEMBL7933489

CCCC1(CCC)CC(Oc2ccccc2)CC(CCC)(CCC)N1ON1C(CCC)(CCC)CC(Oc2ccccc2)CC1(CCC)CCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.41
SLC6A3 Q01959 2/20 0.41
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
HRH1 P35367 1/20 0.38
KDM1A O60341 2/20 0.37
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
SLC6A4 P31645 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.35
DRD2 P14416 3/20 0.33
DRD4 P21917 3/20 0.33
DRD3 P35462 3/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2B Q13224 1/20 0.33
FFAR1 O14842 2/20 0.33
AXL P30530 1/20 0.32
TYRO3 Q06418 1/20 0.32
MERTK Q12866 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7935184 0.89 SLC6A3 (0.41) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7933493 0.86 SLC6A2 (0.40) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7935169 0.77 SLC6A2 (0.45) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7935191 0.76 SLC6A2 (0.41) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7933490 0.74 HRH1 (0.37) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7937428 0.72
SCHEMBL17287083 0.68 SLC6A2 (0.50) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL7924954 0.68
SCHEMBL18200131 0.67 CARM1 (0.49) SLC6A2SLC6A3CARM1PRMT6HRH1
SCHEMBL562024 0.67 SLC6A2 (0.45) SLC6A2SLC6A3CARM1PRMT6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6265469-B1 BLEND CONTAINING A STERIC HINDERED PIPERIDINYLOXY COMPOUND DU PONT WIREX LTD (TW) 2001-07-24 US disclosed