Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD4 | P21917 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933493 | 0.88 | SLC6A2 (0.40) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL7935184 | 0.84 | SLC6A3 (0.41) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL562024 | 0.78 | SLC6A2 (0.45) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL7933489 | 0.76 | SLC6A2 (0.41) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL7935189 | 0.71 | HRH1 (0.39) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| Pyridine SCHEMBL27642701 | 0.71 | GAA (0.41) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL17287083 | 0.69 | SLC6A2 (0.50) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL4797945 | 0.69 | TSHR (0.60) | CARM1PRMT6 | |
| SCHEMBL6754518 | 0.68 | SLC6A2 (0.45) | SLC6A2SLC6A3CARM1PRMT6HRH1 | |
| SCHEMBL7935169 | 0.68 | SLC6A2 (0.45) | SLC6A2SLC6A3CARM1PRMT6HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265469-B1 | BLEND CONTAINING A STERIC HINDERED PIPERIDINYLOXY COMPOUND | DU PONT WIREX LTD (TW) | 2001-07-24 | — | — | US | disclosed |