SCHEMBL7933544

SCHEMBL7933544

CCOc1c(CCC(=O)OCCO)cc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RXRA P19793 8/20 0.42
PPARG P37231 7/20 0.42
RARG P13631 3/20 0.42
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
VCAM1 P19320 3/20 0.34
ELANE P08246 1/20 0.33
CD69 Q07108 1/20 0.33
MGLL Q99685 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7941195 0.89 CYP4F2 (0.40) PPARGCYP4F2CYP4A11ELANECD69
SCHEMBL8433322 0.88 RXRA (0.43) RXRAPPARGRARGVCAM1ELANE
SCHEMBL8397208 0.88 RARG (0.36) RXRAPPARGRARGCYP4F2CYP4A11
SCHEMBL7943101 0.83 ALOX5 (0.37) RXRAPPARGRARGCYP4F2CYP4A11
SCHEMBL7941206 0.83 VCAM1 (0.39) CYP4F2CYP4A11VCAM1MGLL
SCHEMBL7933690 0.83 CYP4F2 (0.44) CYP4F2CYP4A11VCAM1MGLL
SCHEMBL7786441 0.82 RXRA (0.49) RXRAPPARGRARGVCAM1ELANE
SCHEMBL7942330 0.82 CYP4F2 (0.46) CYP4F2CYP4A11MGLL
SCHEMBL8430289 0.81 CYP4F2 (0.38) CYP4F2CYP4A11VCAM1
SCHEMBL7940443 0.81 VCAM1 (0.37) RXRAPPARGRARGCYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed