SCHEMBL7933602

SCHEMBL7933602

Cc1cc(C(C)C)cc(O)c1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.61
GABRB2 P47870 1/20 0.61
TRPA1 O75762 3/20 0.56
PTGS1 P23219 2/20 0.56
CACNA1C Q13936 1/20 0.56
PTGS2 P35354 1/20 0.46
BCL2 P10415 1/20 0.41
BCL2L1 Q07817 1/20 0.41
MCL1 Q07820 1/20 0.41
BCL2L2 Q92843 1/20 0.41
RNASEH1 O60930 1/20 0.41
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
SELL P14151 1/20 0.40
SELP P16109 1/20 0.40
SELE P16581 1/20 0.40
TYR P14679 3/20 0.39
HTT P42858 3/20 0.39
ALDH1A1 P00352 2/20 0.39
ALOX12 P18054 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2754950 0.87 PTGS1 (0.55) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL6346880 0.85 GABRA1 (0.73) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL25505919 0.82 GABRA1 (0.47) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL6943696 0.79 GABRA1 (0.65) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL30467045 0.79 GABRA1 (0.65) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL1487378 0.79 PTGS1 (0.54) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL18778629 0.79 PTGS1 (0.44) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL13581438 0.79 USP2 (0.46) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL20193726 0.78 SELL (0.45) GABRA1GABRB2TRPA1PTGS1CACNA1C
SCHEMBL24507824 0.77 PTGS1 (0.43) GABRA1GABRB2TRPA1PTGS1CACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013092427-A2 ANTIMICROBIAL METHOD AND COMPOSITION UNILEVER N.V. (NL) 2013-06-27 WO claimed
WO-2013083585-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2013-06-13 WO claimed
US-20230382926-A1 COMPOUNDS AND USES THEREOF THE UNIVERSITY OF THE WEST INDIES (TT) 2023-11-30 US disclosed
US-8962244-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2015-02-24 US disclosed
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR UNIVERSITY OF MASSACHUSETTS (US) 2013-08-22 US disclosed
WO-2013092427-A2 ANTIMICROBIAL METHOD AND COMPOSITION UNILEVER N.V. (NL) 2013-06-27 WO disclosed
WO-2013092427-A2 ANTIMICROBIAL METHOD AND COMPOSITION UNILEVER N.V. (NL) 2013-06-27 WO disclosed
WO-2013083585-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2013-06-13 WO disclosed
WO-2013083585-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2013-06-13 WO disclosed
US-8377639-B2 Compounds for modulating RNA binding proteins and uses therefor UNIVERSITY OF MASSACHUSETTS (US) 2013-02-19 US disclosed
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2011-03-17 US disclosed
CN-101313021-A Radiation absorbing compositions, methods and articles made by applying such compositions MILLIKEN & CO (US) 2008-11-26 CN disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130217685-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 GABRA1 1857/4885GABRB2 2445/4885TRPA1 754/4885
US-20230382926-A1 COMPOUNDS AND USES THEREOF CFTR, CCL11, CEL GABRA1 2548/4885GABRB2 3275/4885TRPA1 448/4885
US-20110065704-A1 COMPOUNDS FOR MODULATING RNA BINDING PROTEINS AND USES THEREFOR TIA1, ZFP3, RBM3 GABRA1 1857/4885GABRB2 2445/4885TRPA1 754/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.