Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28337159 | 0.82 | ACE (0.43) | STS | |
| SCHEMBL26891446 | 0.79 | HSD11B1 (0.35) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL803672 | 0.77 | SIGMAR1 (0.59) | KCNH2BCHEACHEHTR2C | |
| SCHEMBL19734754 | 0.76 | BCHE (0.56) | L3MBTL1BCHEKMT2AACHE | |
| SCHEMBL6818563 | 0.75 | KMT2A (0.56) | L3MBTL1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL7507555 | 0.75 | SIGMAR1 (0.51) | KCNH2BCHEACHEHTR2C | |
| SCHEMBL20487341 | 0.75 | NFKB1 (0.39) | KMT2AFKBP1A | |
| SCHEMBL20481011 | 0.75 | NFKB1 (0.39) | KMT2AFKBP1A | |
| SCHEMBL7936884 | 0.75 | KMT2A (0.56) | L3MBTL1KMT2AHDAC1HDAC8HDAC6 | |
| SCHEMBL3815654 | 0.75 | SIGMAR1 (0.51) | KCNH2BCHEACHEHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |