SCHEMBL7933823

SCHEMBL7933823

O=C1CCC(=O)N1C(Cl)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.43
PKM P14618 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRM3 P20309 1/20 0.43
TSHR P16473 1/20 0.41
PARL Q9H300 3/20 0.38
SLC1A2 P43004 1/20 0.38
RAF1 P04049 1/20 0.38
MAPK3 P27361 1/20 0.38
MAP3K8 P41279 1/20 0.38
MAP2K1 Q02750 1/20 0.38
KMT2A Q03164 3/20 0.37
ATM Q13315 1/20 0.37
POLB P06746 1/20 0.36
MEN1 O00255 2/20 0.35
TACR1 P25103 1/20 0.35
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7923888 0.86 ALDH1A1 (0.39) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL7774093 0.77 TSHR (0.42) ALDH1A1PKMTSHRATMHPGD
SCHEMBL11061023 0.75 TDP1 (0.46) ALDH1A1TSHRPOLBHPGDLMNA
SCHEMBL15581083 0.75 ALDH1A1 (0.47) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL40439 0.75 ALDH1A1 (0.53) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL9632134 0.72 LMNA (0.53) ALDH1A1PKMCHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL11066275 0.72 TDP1 (0.43) ALDH1A1TSHRPOLBHPGDLMNA
SCHEMBL6929886 0.71 ALDH1A1 (0.43) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL9607830 0.71 ALDH1A1 (0.44) ALDH1A1PKMCHRM2CHRM4CHRM5
SCHEMBL22207807 0.69 ALDH1A1 (0.46) ALDH1A1PKMCHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0800551-B1 SULFUR-VULCANIZED RUBBER COMPOSITIONS COMPRISING SUBSTITUTED SUCCINIMIDE COMPOUNDS AKZO NOBEL NV (NL) 2001-06-13 EP claimed