SCHEMBL7933923

SCHEMBL7933923

CCc1cc(CCC(=O)OCCO)cc(C(C)(C)CC)c1O

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.39
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
APP P05067 2/20 0.37
HSPA5 P11021 1/20 0.37
KMT2A Q03164 3/20 0.36
GAA P10253 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
CNR2 P34972 1/20 0.33
MGLL Q99685 1/20 0.33
MEN1 O00255 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8597184 0.91 MGLL (0.40) ALOX5CYP4F2CYP4A11APPKMT2A
SCHEMBL7943346 0.91 ALOX5 (0.38) ALOX5CYP4F2CYP4A11APPHSPA5
SCHEMBL7940204 0.90 HSPA5 (0.48) ALOX5CYP4F2CYP4A11APPHSPA5
SCHEMBL7945011 0.89 GAA (0.48) ALOX5CYP4F2CYP4A11APPKMT2A
SCHEMBL8598476 0.88 CYP4F2 (0.42) ALOX5CYP4F2CYP4A11APPKMT2A
SCHEMBL7943348 0.88 CNR2 (0.41) ALOX5CNR2MGLL
SCHEMBL7942509 0.86 KMT2A (0.39) ALOX5CYP4F2CYP4A11APPKMT2A
SCHEMBL27653761 0.81 APP (0.53) ALOX5CYP4F2CYP4A11APPTDP1
SCHEMBL3809037 0.81 HSPA5 (0.46) ALOX5HSPA5KMT2AGAAMEN1
SCHEMBL1434838 0.81 HSPA5 (0.49) ALOX5APPHSPA5KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed