SCHEMBL7943346

SCHEMBL7943346

CCc1cc(CCC(=O)OCCO)cc(C(C)(C)CC(C)(C)C)c1O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.38
CYP4F2 P78329 1/20 0.37
CYP4A11 Q02928 1/20 0.37
APP P05067 2/20 0.36
HSPA5 P11021 1/20 0.35
GAA P10253 2/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
MGLL Q99685 1/20 0.34
CNR2 P34972 4/20 0.34
CNR1 P21554 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7933923 0.91 ALOX5 (0.39) ALOX5CYP4F2CYP4A11APPHSPA5
SCHEMBL7944692 0.88 GAA (0.47) ALOX5APPGAAKMT2ACYP3A4
SCHEMBL7940204 0.88 HSPA5 (0.48) ALOX5CYP4F2CYP4A11APPHSPA5
SCHEMBL7943348 0.88 CNR2 (0.41) ALOX5MGLLCNR2CNR1
SCHEMBL7940280 0.87 ALOX5 (0.39) ALOX5CYP4F2CYP4A11APPGAA
SCHEMBL7942500 0.86 KMT2A (0.37) ALOX5CYP4F2CYP4A11APPGAA
SCHEMBL8597184 0.84 MGLL (0.40) ALOX5CYP4F2CYP4A11APPGAA
SCHEMBL3805391 0.82 HSPA5 (0.44) HSPA5GAAKMT2ACYP3A4SMN1; SMN2
SCHEMBL7942304 0.81 HSPA5 (0.41) HSPA5GAAKMT2A
SCHEMBL2917130 0.81 HSPA5 (0.43) CYP4F2CYP4A11HSPA5GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
EP-0861847-A2 Stabilizer composition and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-09-02 EP disclosed