Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922042 | 0.90 | L3MBTL1 (0.40) | MAPTKDM4EENPP2ACACBPRSS1 | |
| SCHEMBL30956024 | 0.90 | L3MBTL1 (0.44) | MAPTKDM4EENPP2PRSS1L3MBTL1 | |
| SCHEMBL7934072 | 0.83 | KDM4E (0.43) | MAPTKDM4ERECQLRAB9AACACB | |
| SCHEMBL8339774 | 0.82 | MAPT (0.52) | MAPTKDM4ERECQLRAB9APRSS1 | |
| SCHEMBL28259547 | 0.82 | MAPK1 (0.46) | KDM4EENPP2L3MBTL1 | |
| SCHEMBL2772370 | 0.82 | LTA4H (0.55) | KDM4ERAB9ALTA4H | |
| SCHEMBL2413751 | 0.82 | LTA4H (0.55) | MAPTKDM4ERAB9AL3MBTL1LTA4H | |
| SCHEMBL7931088 | 0.82 | NQO1 (0.36) | MAPTENPP2LTA4H | |
| SCHEMBL28259878 | 0.82 | TSHR (0.41) | MAPTRECQLENPP2RAB9APKM | |
| SCHEMBL6341253 | 0.81 | THRA (0.48) | KDM4ERECQLACACBL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864076-A | glucosylceramide synthase inhibitors | 建新公司 | 2018-11-23 | — | — | CN | disclosed |
| EP-1140896-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | Takeda Chemical Industries, Ltd. (JP) | 2001-10-10 | — | — | EP | disclosed |
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| WO-2000037455-A1 | BENZOTHIEPIN-ANILIDE DERIVATIVES, THEIR PRODUCTION AND THEIR USE FOR ANTAGONIZING CCR-5 | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2000-06-29 | — | — | WO | disclosed |