Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463093 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL408760 | 0.82 | KMT2A (0.44) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL14569693 | 0.80 | SIGMAR1 (0.51) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL23954099 | 0.79 | HSD17B10 (0.37) | SLC6A4SLC6A3KDM4ELMNATDP1 | |
| SCHEMBL3113817 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2APOLBDPP7 | |
| SCHEMBL5673787 | 0.78 | SIGMAR1 (0.52) | MEN1KMT2ASIGMAR1SLC6A3 | |
| SCHEMBL14558149 | 0.76 | MEN1 (0.48) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL3773844 | 0.75 | SIGMAR1 (0.39) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL13013957 | 0.75 | LMNA (0.42) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL27138554 | 0.74 | MEN1 (0.64) | MEN1KMT2ASIGMAR1SLC6A3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011367-A2 | BIMODAL LIGANDS WITH MACROCYCLIC AND ACYCLIC BINDING MOIETIES, COMPLEXES AND COMPOSITIONS THEREOF, AND METHODS OF USING | ILLINOIS INSTITUTE OF TECHNOLOGY (US) | 2010-01-28 | — | — | WO | disclosed |