SCHEMBL7934548

SCHEMBL7934548

CC=CC(=O)OCC(O)COc1cc[c]cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
POLB P06746 2/20 0.44
LMNA P02545 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
CYP1A2 P05177 2/20 0.43
ALDH1A1 P00352 2/20 0.37
PLA2G4B P0C869 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9177632 0.86 MEN1 (0.49) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL3194813 0.83 LMNA (0.48) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL721027 0.82 CYP1A2 (0.48) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL941494 0.82 MAPT (0.47) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL11519941 0.82 MAPK1 (0.49) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL59992 0.81 HTT (0.52) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL7517507 0.81 POLB (0.46) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL349426 0.80 POLB (0.44) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL5081247 0.80 KMT2A (0.50) MAPTPOLBLMNANPSR1SMN1; SMN2
SCHEMBL10336222 0.80 POLB (0.44) MAPTPOLBLMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5846075-A One package, shelf-stable photo-curable band cement BISCO, INC. (US) 1998-12-08 US claimed
CN-101001886-B Redox curing-type nonaqueous curable composition KURARAY MEDICAL INC 2011-07-13 CN disclosed
CN-101163766-B Adhesive composition KURARAY MEDICAL INC 2011-05-04 CN disclosed
CN-101163766-A Adhesive composition KURARAY MEDICAL INC (JP) 2008-04-16 CN disclosed
CN-101001886-A Redox curing-type nonaqueous curable composition KURARAY MEDICAL INC (JP) 2007-07-18 CN disclosed
US-6262208-B1 NO ELUTION, WATER-RETAINING CAPABILITY, OXYGEN PERMEABILITY, TRANSPARENCY, RESISTANCE TO DEPOSITION, MECHANICAL STRENGTH, FLEXIBILITY, SAFETY, DURABILITY, CORRECTION OF VISUAL ACUITY, AND COMFORT DURING WEAR KURARAY CO., LTD. (JP) 2001-07-17 US disclosed
US-5865623-A POLYETHER-ACRYLATE BISCO, INC. (US) 1999-02-02 US disclosed
US-5846075-A One package, shelf-stable photo-curable band cement BISCO, INC. (US) 1998-12-08 US disclosed
EP-0584372-A1 BIOACTIVE CEMENT NIPPON ELECTRIC GLASS COMPANY, Limited (JP) 1994-03-02 EP disclosed
EP-0047971-A1 Mineral particles, process for their preparation and dental materials containing them DMG - Dental-Material-Gesellschaft mbH (DE) 1982-03-24 EP disclosed