Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9850746 | 0.92 | ADRB3 (0.44) | MAPK1TSHRHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL9177632 | 0.90 | MEN1 (0.49) | KDM4ESMN1; SMN2L3MBTL1LMNAPOLB | |
| SCHEMBL10931458 | 0.90 | MAOA (0.43) | MAPK1TSHRHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL17885758 | 0.83 | KDM4E (0.47) | MAPK1TSHRHIF1AKDM4EL3MBTL1 | |
| SCHEMBL11650141 | 0.82 | THRB (0.49) | MAPK1TSHRHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL13423344 | 0.82 | THRB (0.49) | MAPK1TSHRHIF1AKDM4ESMN1; SMN2 | |
| SCHEMBL21081984 | 0.82 | CYP1A2 (0.58) | KDM4ESMN1; SMN2LMNAADRB2ADRB1 | |
| SCHEMBL3194813 | 0.82 | LMNA (0.48) | TSHRKDM4ESMN1; SMN2LMNAPOLB | |
| SCHEMBL7934548 | 0.82 | MAPT (0.44) | KDM4ESMN1; SMN2LMNAPOLBMAPT | |
| SCHEMBL721027 | 0.81 | CYP1A2 (0.48) | MAPK1SMN1; SMN2GAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156766-A | ACRYLATES AND/OR METHACRYLATES, P-T-BUTYLBENZOYL PEROXIDE, AMINE ACCELERATOR; DENTAL RESTORATIVE MATERIAL, HEAT RESISTANT | JOHNSON & JOHNSON (US) | 1979-05-29 | — | — | US | disclosed |