Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20794613 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12051770 | 0.81 | PKM (0.60) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1016659 | 0.79 | ALDH1A1 (0.60) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28406303 | 0.79 | LMNA (0.54) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6028329 | 0.78 | HSD17B10 (0.59) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30104761 | 0.78 | HSD17B10 (0.59) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7816315 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL15923334 | 0.77 | ALDH1A1 (0.57) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7812949 | 0.77 | LMNA (0.54) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL12062757 | 0.77 | KMT2A (0.51) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242500-B1 | Intercalates and exfoliates formed with long chain (C6+) or aromatic matrix polymer-compatible monomeric, oligomeric or polymeric intercalant compounds, and composite materials containing same | AMCOL INTERNATIONAL CORPORATION | 2001-06-05 | — | — | US | disclosed |
| US-6124365-A | USEFUL AS PLASTICIZERS AND FOR PROVIDING INCREASED VISCOSITY AND ELASTICITY TO THERMOPLASTIC AND THERMOSETTING POLYMERS, E.G., FOR PLASTICIZING POLYVINYL CHLORIDE; FOR FOOD WRAP HAVING IMPROVED GAS IMPERMEABILITY | AMCOL INTERNATIOANL CORPORATION (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0846662-A2 | Intercalates and exfoliates, their process of manufacture and composites containing them | AMCOL INTERNATIONAL CORPORATION (US) | 1998-06-10 | — | — | EP | disclosed |