Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929135 | 0.90 | MAPT (0.41) | LPAR1LPAR5L3MBTL1TACR1LTA4H | |
| SCHEMBL9558435 | 0.89 | TTR (0.40) | LPAR1LPAR5TTRL3MBTL1RAB9A | |
| SCHEMBL9560804 | 0.86 | TTR (0.39) | LPAR1LPAR5TTRL3MBTL1RAB9A | |
| SCHEMBL9560878 | 0.86 | LMNA (0.41) | LPAR1LPAR5TTRL3MBTL1RAB9A | |
| SCHEMBL10758162 | 0.84 | LPAR1 (0.37) | LPAR1LPAR5TTRL3MBTL1RAB9A | |
| SCHEMBL10837117 | 0.83 | NPC1 (0.38) | LPAR1LPAR5TTRRAB9ATACR1 | |
| SCHEMBL7930444 | 0.83 | LPAR1 (0.40) | LPAR1LPAR5TTRL3MBTL1RAB9A | |
| SCHEMBL10836849 | 0.83 | TTR (0.36) | TTRL3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL10346793 | 0.82 | LPAR1 (0.44) | LPAR1LPAR5TTRALDH1A1KDM4E | |
| SCHEMBL9558410 | 0.81 | TACR1 (0.44) | LPAR1LPAR5TTRTACR1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37087-E1 | 1-(4-ETHOXYPHENYL)-4-(4-FLUORO-3-PHENOXYPHENYL)-1 -TRIFLUOROMETHYLBUTANE OR 1-(4-ETHOXY-3-FLUOROPHENYL)-4-(3-PHENOXYPHENYL)-1-TRIFLUOROMETHYLBUTANE, FOR EXAMPLE; COMBATS INSECTS AND MITES | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | claimed |
| US-4791123-A | MITICIDES | SCHERING AKT. (DE) | 1988-12-13 | — | — | US | claimed |