Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560793 | 0.91 | NR4A1 (0.36) | LPAR1LPAR5NR3C2CHRM3TTR | |
| SCHEMBL9560585 | 0.90 | MAPK14 (0.39) | SMN1; SMN2FFAR1 | |
| SCHEMBL9560403 | 0.90 | NR3C2 (0.37) | LMNALPAR1LPAR5NR3C2CHRM3 | |
| SCHEMBL9560512 | 0.90 | LMNA (0.40) | LMNAMAPTTP53L3MBTL1SMN1; SMN2 | |
| SCHEMBL9561340 | 0.90 | LTA4H (0.38) | — | |
| SCHEMBL9560709 | 0.89 | L3MBTL1 (0.36) | LMNAALDH1A1CHRM3TTRL3MBTL1 | |
| SCHEMBL9560338 | 0.89 | ALOX5 (0.33) | LPAR1LPAR5NR3C2RAB9AFFAR1 | |
| SCHEMBL9560800 | 0.88 | SMN1; SMN2 (0.35) | LPAR1LPAR5NR3C2CHRM3TTR | |
| SCHEMBL7934909 | 0.86 | LPAR1 (0.38) | LMNAALDH1A1KDM4ELPAR1LPAR5 | |
| SCHEMBL9558435 | 0.86 | TTR (0.40) | ALDH1A1KDM4ELPAR1LPAR5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |