Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9560696 | 0.91 | TACR1 (0.36) | TTRLPAR1LPAR5RAB9ACHRM3 | |
| SCHEMBL9561293 | 0.90 | LMNA (0.35) | TTRLPAR1LPAR5L3MBTL1SMN1; SMN2 | |
| SCHEMBL9560787 | 0.90 | L3MBTL1 (0.34) | TTRL3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL9560321 | 0.90 | MAPT (0.40) | TTRL3MBTL1ALDH1A1KDM4ELTA4H | |
| SCHEMBL9560860 | 0.90 | CHRM5 (0.36) | TTRLTA4H | |
| SCHEMBL9560383 | 0.89 | TTR (0.34) | TTRLPAR1LPAR5RAB9AALDH1A1 | |
| SCHEMBL7934909 | 0.86 | LPAR1 (0.38) | TTRLPAR1LPAR5L3MBTL1RAB9A | |
| SCHEMBL9558435 | 0.86 | TTR (0.40) | TTRLPAR1LPAR5L3MBTL1RAB9A | |
| SCHEMBL9560878 | 0.85 | LMNA (0.41) | TTRLPAR1LPAR5L3MBTL1RAB9A | |
| SCHEMBL9637902 | 0.85 | L3MBTL1 (0.33) | TTRL3MBTL1LTA4HLMNAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225607-A | Multistage etherification or dehydrohalogenation and reductive dechlorination | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-07-06 | — | — | US | disclosed |
| US-5196610-A | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-03-23 | — | — | US | disclosed |
| EP-0211561-B1 | INSECTICIDAL ETHERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |
| EP-0211561-A1 | Insecticidal ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-02-25 | — | — | EP | disclosed |