Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 17/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 17/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882797 | 0.82 | SLC6A4 (0.39) | SLC6A2SLC6A4SLC6A3KDM4CCYP2D6 | |
| SCHEMBL9027067 | 0.81 | SLC6A4 (0.38) | SLC6A2SLC6A4SLC6A3KDM4CCYP3A4 | |
| SCHEMBL8291781 | 0.81 | SLC6A3 (0.46) | SLC6A2SLC6A4SLC6A3KDM4CCYP2D6 | |
| SCHEMBL7765670 | 0.78 | SLC6A3 (0.39) | SLC6A2SLC6A4SLC6A3KDM4CCYP2D6 | |
| SCHEMBL6957304 | 0.78 | SLC6A2 (0.50) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL7077339 | 0.77 | SLC6A4 (0.57) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL6950573 | 0.77 | TACR1 (0.39) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4630125 | 0.77 | SLC6A3 (0.37) | SLC6A2SLC6A4SLC6A3KDM4CMEN1 | |
| SCHEMBL4630541 | 0.77 | SLC6A3 (0.37) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL4631674 | 0.77 | SLC6A2 (0.37) | SLC6A2SLC6A4SLC6A3KDM4CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242438-B1 | 3-Azetidinylalkylpiperidines or -pyrrolidines as tachykinin antagonists | PFIZER INC. | 2001-06-05 | — | — | US | disclosed |