Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4115867 | 0.90 | MEN1 (0.44) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL11980111 | 0.87 | MAOA (0.50) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL775694 | 0.87 | MAOA (0.50) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL27902166 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28209874 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL28033978 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8516000 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL21603033 | 0.87 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL15114863 | 0.86 | MEN1 (0.55) | MEN1KMT2ANPSR1ALDH1A1MAPT | |
| SCHEMBL2414534 | 0.85 | ALDH1A1 (0.53) | ALDH1A1MAPTSMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242654-B1 | REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND | MITSUI CHEMICALS, INC. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-1013629-A1 | Preparation process of fluorine subsituted aromatic compound | Mitsui Chemicals, Inc. (JP) | 2000-06-28 | — | — | EP | disclosed |