Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7938806 | 0.85 | TNKS2 (0.32) | PGR | |
| Hydrochloric Acid SCHEMBL7938701 | 0.81 | IKBKB (0.32) | — | |
| Hydrochloric Acid SCHEMBL7936138 | 0.73 | BCL2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27521258 | 0.73 | ACHE (0.37) | PGR | |
| Hydrochloric Acid SCHEMBL27566934 | 0.72 | ACHE (0.36) | PGR | |
| Hydrochloric Acid SCHEMBL27546010 | 0.71 | ACHE (0.35) | PGR | |
| Hydrochloric Acid SCHEMBL27520463 | 0.71 | ACHE (0.35) | PGR | |
| Hydrochloric Acid SCHEMBL7926764 | 0.69 | ACHE (0.32) | — | |
| Hydrochloric Acid SCHEMBL27566935 | 0.69 | ACHE (0.36) | PGR | |
| Hydrochloric Acid SCHEMBL27546012 | 0.69 | ACHE (0.36) | PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |