SCHEMBL7935644

SCHEMBL7935644

N#Cc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.67
CA12 O43570 4/20 0.67
CA9 Q16790 4/20 0.67
CA3 P07451 1/20 0.67
CA6 P23280 1/20 0.67
CA14 Q9ULX7 1/20 0.67
MMP3 P08254 1/20 0.59
CA1 P00915 5/20 0.50
GAA P10253 1/20 0.50
PKM P14618 1/20 0.50
MAOA P21397 1/20 0.49
MAOB P27338 1/20 0.49
LMNA P02545 1/20 0.46
ENPP2 Q13822 1/20 0.45
P4HB P07237 1/20 0.45
CYP19A1 P11511 2/20 0.44
NAMPT P43490 1/20 0.43
ELANE P08246 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8514633 0.89 CA2 (0.59) CA2CA12CA9CA3CA6
Water SCHEMBL6425932 0.84 GAA (0.64) CA2CA12CA9CA3CA14
4-Cyanophenol SCHEMBL28811803 0.82 CA2 (1.00) CA2CA12CA9CA3CA6
4-Cyanophenol SCHEMBL27294505 0.82 CA2 (1.00) CA2CA12CA9CA3CA6
SCHEMBL124022 0.82 GAA (0.67) CA2CA12CA9CA3CA14
4-Cyanophenol SCHEMBL50814 0.82
SCHEMBL18838 0.82 GAA (0.67) CA2CA12CA9CA3CA14
SCHEMBL29724901 0.82 GAA (0.67) CA2CA12CA9CA3CA14
SCHEMBL3792342 0.82 GAA (0.67) CA2CA12CA9CA3CA14
SCHEMBL161783 0.81 HTR6 (0.61) CA2CA12CA9CA1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6242654-B1 REACTING A PHENOLATE COMPOUND WITH AN ORGANIC FLUORINATING AGENT TO PREPARE A FLUORINE SUBSTITUTED AROMATIC COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-06-05 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0451007-B1 Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy FOURNIER IND & SANTE (FR) 1995-11-08 EP disclosed
CN-1026323-C Sulphonylphenyl-beta-D-thioxylosides and their use as anti-inflammatory agents FOURNIER IND & SANTE (FR) 1994-10-26 CN disclosed
US-5100913-A Venous antithrombotics FOURNIER INDUSTRIE ET SANTE (FR) 1992-03-31 US disclosed
CN-1055364-A New sulfonyl-phenyl-β-D-sulfo-xyloside prepares their method and their purposes in medical treatment FOURNIER IND & SANTE (FR) 1991-10-16 CN disclosed
EP-0451007-A1 Sulphonylphenyl-beta-D-thioxylosides, process for their preparation and their use in therapy FOURNIER INDUSTRIE ET SANTE (FR) 1991-10-09 EP disclosed