Butylbenzyl

Butylbenzyl

SCHEMBL7935812

CCCCc1ccccc1.Fc1ccccc1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.50
SIGMAR1 Q99720 2/20 0.50
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CHRM2 P08172 1/20 0.48
HTR1A P08908 1/20 0.48
ADRA2A P08913 1/20 0.48
CHRM1 P11229 1/20 0.48
DRD1 P21728 1/20 0.48
SLC6A2 P23975 1/20 0.48
SLC6A4 P31645 1/20 0.48
ADRA1A P35348 1/20 0.48
OPRM1 P35372 1/20 0.48
DRD3 P35462 1/20 0.48
SLC6A3 Q01959 1/20 0.48
HSD11B1 P28845 1/20 0.47
ALDH1A1 P00352 1/20 0.47
HPGD P15428 1/20 0.47
HSD17B10 Q99714 1/20 0.47
FFAR1 O14842 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorobenzene SCHEMBL27881047 0.94 KCNH2 (0.58) KCNH2SIGMAR1ADRA2ASLC6A2SLC6A4
Fluorobenzene SCHEMBL28265021 0.92 KCNH2 (0.61) KCNH2SIGMAR1CHRM2ADRA2ACHRM1
Fluorobenzene SCHEMBL28868670 0.89 LPL (0.55) KCNH2SIGMAR1CHRM2ADRA2ACHRM1
Butylbenzyl SCHEMBL22716183 0.89 SIGMAR1 (0.59) KCNH2SIGMAR1CHRM2HTR1AADRA2A
Butylbenzyl SCHEMBL16051 0.89 SIGMAR1 (0.59) KCNH2SIGMAR1CHRM2HTR1AADRA2A
Butylbenzyl SCHEMBL3229215 0.89 SIGMAR1 (0.59) KCNH2SIGMAR1CHRM2HTR1AADRA2A
Butylbenzyl SCHEMBL1357980 0.86 SIGMAR1 (0.57) KCNH2SIGMAR1CA1CA2CHRM2
Butylbenzyl SCHEMBL363180 0.86 SIGMAR1 (0.57) KCNH2SIGMAR1CA1CA2CHRM2
Butylbenzyl SCHEMBL7713579 0.86 SIGMAR1 (0.57) KCNH2SIGMAR1CA1CA2CHRM2
Butylbenzyl SCHEMBL9545214 0.86 SIGMAR1 (0.57) KCNH2SIGMAR1CHRM2HTR1AADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6307113-B1 CATALYST COMPOSITION FORMED BY INCLUDING IN SAID MEDIUM A COMBINATION OF (I) A SHAPE SELECTIVE HY OR HMOR ZEOLITE CATALYST, AND (II) AT LEAST ONE LEWIS ACID ALBEMARLE CORPORATION 2001-10-23 US claimed