Fluorobenzene

Fluorobenzene

SCHEMBL28868670

CCCCCc1ccc(CCCCC)cc1.Fc1ccccc1

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPL P06858 4/20 0.55
LIPG Q9Y5X9 4/20 0.55
HTR2A P28223 2/20 0.54
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorobenzene SCHEMBL27881047 0.96 KCNH2 (0.58) LPLLIPGHTR2AESR1ADRA2A
Fluorobenzene SCHEMBL28265021 0.94 KCNH2 (0.61) LPLLIPGHTR2AESR1ADRA2A
Butylbenzyl SCHEMBL7935812 0.89 KCNH2 (0.50) ADRA2ASLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL1430472 0.89 ALDH1A1 (0.59) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL9717309 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL13564082 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL2615718 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL2615717 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL3941872 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A
SCHEMBL27362553 0.87 ESR1 (0.63) LPLLIPGHTR2AESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106589349-B Bi-phthalonitrile resin of main chain s-triazine structure containing triaryl and preparation method thereof 大连理工大学 2019-01-08 CN claimed
CN-107201034-B A kind of anti-reflection polymer composite film and preparation method thereof with elemental oxygen degradation resistant 中国科学院宁波材料技术与工程研究所 2019-10-18 CN disclosed