Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7935505 | 0.82 | KDM4E (0.34) | KDM4E | |
| Hydrochloric Acid SCHEMBL7936805 | 0.81 | KDM4E (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL7938818 | 0.78 | KDM4E (0.38) | KDM4E | |
| Hydrochloric Acid SCHEMBL7935307 | 0.77 | ADRA2A (0.30) | — | |
| Hydrochloric Acid SCHEMBL7926450 | 0.76 | KDM4E (0.33) | KDM4E | |
| Hydrochloric Acid SCHEMBL6891531 | 0.71 | KDM4E (0.36) | KDM4E | |
| Hydrochloric Acid SCHEMBL6886402 | 0.71 | KDM4E (0.36) | KDM4E | |
| Hydrochloric Acid SCHEMBL6891722 | 0.71 | KDM4E (0.36) | KDM4E | |
| Hydrochloric Acid SCHEMBL7926973 | 0.70 | KDM4E (0.35) | KDM4E | |
| Hydrochloric Acid SCHEMBL7933117 | 0.69 | ALOX5 (0.35) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6184402-B1 | RESOLUTION OF A STEREOISOMERIC MIXTURE OF SPECIFIC METALLOCENE COMPLEXES BRIDGED WITH A TRANSITION METAL HAVING AN OXYGEN BOND ATTACHED, I.E., A MU-OXO COMPLEX; HYDROLYSIS IN THE PRESENCE OF A BASE; SEPARATION OF MESO FORM FROM MIXES | CHISSO CORPORATION (JP) | 2001-02-06 | — | — | US | disclosed |