Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27459561 | 0.82 | NFE2L2 (0.50) | LCKNFE2L2ALOX5PTGS1PTGS2 | |
| SCHEMBL14051358 | 0.82 | TYR (0.46) | CNR2TYRCYP3A4ATMMAPT | |
| SCHEMBL20931111 | 0.78 | CNR2 (0.37) | CNR2TYRCYP3A4ATMMAPT | |
| SCHEMBL17934472 | 0.78 | TDP1 (0.56) | MAPTCYP2C9PTGS1ALDH1A1APP | |
| SCHEMBL15576945 | 0.78 | PNMT (0.36) | CNR2 | |
| SCHEMBL335941 | 0.78 | CNR2 (0.50) | CNR2TYRLCKCYP3A4ATM | |
| SCHEMBL335942 | 0.78 | CNR2 (0.50) | CNR2TYRLCKCYP3A4ATM | |
| SCHEMBL29033283 | 0.78 | CNR2 (0.50) | CNR2TYRLCKCYP3A4ATM | |
| SCHEMBL28883947 | 0.77 | TDP1 (0.50) | LCKCYP3A4CYP2D6MAPTCYP2C9 | |
| SCHEMBL11518269 | 0.76 | HDAC4 (0.51) | CNR2TYRLCKCYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2001507741-A | — | — | 2001-06-12 | — | — | JP | claimed |
| EP-0951498-A1 | MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME | Althin Medical, Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| WO-1998029478-A1 | MELT-SPUN POLYSULFONE SEMIPERMEABLE MEMBRANES AND METHODS FOR MAKING THE SAME | ALTHIN MEDICAL, INC. (US) | 1998-07-09 | — | — | WO | claimed |