Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 19/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 19/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731892 | 0.80 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL7505048 | 0.80 | CYP11B1 (0.52) | CYP11B1CYP11B2 | |
| SCHEMBL7714185 | 0.79 | CYP11B1 (0.44) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL16731850 | 0.78 | GPBAR1 (0.46) | CYP11B1CYP11B2 | |
| SCHEMBL31379324 | 0.73 | CYP2A6 (0.44) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL24966825 | 0.72 | ALDH1A1 (0.59) | CYP11B1CYP11B2 | |
| SCHEMBL7714943 | 0.72 | CYP11B1 (0.38) | CYP11B1CYP11B2 | |
| SCHEMBL7714940 | 0.72 | CYP11B1 (0.38) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL6409767 | 0.71 | CYP11B1 (0.64) | CYP11B1CYP11B2CACNA1H | |
| SCHEMBL104710 | 0.68 | TRPV4 (0.52) | CYP11B1CYP11B2CACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |