Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.49 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.35 |
| ▸ | EP300 | Q09472 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409770 | 0.90 | DAO (0.43) | DAOTRPV4CYP11B1CYP11B2S1PR3 | |
| SCHEMBL6417855 | 0.81 | GPR52 (0.37) | DAOCACNA1HS1PR1GPR52 | |
| SCHEMBL7715298 | 0.80 | DAO (0.51) | DAOTRPV4CYP11B1CYP11B2BRS3 | |
| SCHEMBL7454907 | 0.75 | AR (0.39) | KCNJ1KCNH2CACNA1H | |
| SCHEMBL6688212 | 0.73 | TYMP (0.45) | DAOCYP11B1CYP11B2BRS3 | |
| SCHEMBL7715279 | 0.72 | DAO (0.43) | DAOTRPV4KCNJ1KCNH2CYP11B1 | |
| SCHEMBL7743907 | 0.72 | DAO (0.47) | DAOTRPV4CYP11B1CYP11B2GPR52 | |
| Hydrochloric Acid SCHEMBL7745910 | 0.71 | DAO (0.46) | DAOTRPV4CYP11B1CYP11B2GPR52 | |
| SCHEMBL6433917 | 0.71 | DAO (0.46) | DAOTRPV4CYP11B1CYP11B2BRS3 | |
| Hydrochloric Acid SCHEMBL6438009 | 0.70 | DAO (0.45) | DAOTRPV4CYP11B1CYP11B2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |