Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8304229 | 0.99 | BRS3 (0.47) | BRS3OPRM1BCHESCN8ACYP19A1 | |
| SCHEMBL8582845 | 0.85 | SCN8A (0.43) | BRS3OPRM1SCN8ACYP19A1 | |
| SCHEMBL6165590 | 0.79 | SIGMAR1 (0.64) | OPRM1BCHESCN8ASIGMAR1 | |
| SCHEMBL7927442 | 0.79 | FNTA (0.46) | — | |
| SCHEMBL7936033 | 0.78 | KCNH2 (0.48) | — | |
| SCHEMBL7919393 | 0.77 | BRS3 (0.62) | BRS3CYP19A1 | |
| SCHEMBL8106049 | 0.77 | BRS3 (0.46) | BRS3OPRM1CYP19A1ABCG2 | |
| Hydrochloric Acid SCHEMBL8521500 | 0.76 | BRS3 (0.61) | BRS3CYP19A1 | |
| SCHEMBL7129739 | 0.73 | BRS3 (0.52) | BRS3CYP19A1 | |
| SCHEMBL10588302 | 0.73 | BRS3 (0.49) | BRS3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833633-A4 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO INC (US) | 1999-03-24 | — | — | EP | claimed |
| EP-0833633-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | Merck & Co., Inc. (US) | 1998-04-08 | — | — | EP | claimed |