Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.38 |
| ▸ | FNTA | P49354 | 11/20 | 0.34 |
| ▸ | FNTB | P49356 | 11/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 9/20 | 0.34 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7936033 | 0.86 | KCNH2 (0.48) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7927442 | 0.83 | FNTA (0.46) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7936646 | 0.69 | FNTA (0.52) | KCNH2FNTAFNTBPGGT1BPKM | |
| SCHEMBL7937509 | 0.68 | FNTA (0.69) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| Hydrochloric Acid SCHEMBL7939633 | 0.67 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| Hydrochloric Acid SCHEMBL7939637 | 0.67 | FNTA (0.68) | KCNH2FNTAFNTBPGGT1BCYP3A4 | |
| SCHEMBL7937336 | 0.67 | FNTA (0.56) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL7464954 | 0.65 | FNTA (0.45) | KCNH2FNTAFNTBPGGT1B | |
| SCHEMBL8965454 | 0.64 | SLC6A2 (0.45) | PKMALDH1A1GAA | |
| SCHEMBL8298317 | 0.63 | BRS3 (0.48) | BCHEDRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |