Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21480779 | 0.74 | ALDH1A1 (0.38) | ALDH1A1RAB9AMAPTLMNAGAA | |
| SCHEMBL21664133 | 0.68 | HDAC3 (0.34) | — | |
| SCHEMBL21664082 | 0.67 | HDAC3 (0.33) | — | |
| SCHEMBL21663828 | 0.67 | HDAC3 (0.33) | — | |
| SCHEMBL23241641 | 0.64 | — | — | |
| SCHEMBL21689149 | 0.63 | NOS3 (0.39) | LMNANOS3NOS1NOS2 | |
| SCHEMBL14672195 | 0.62 | ALDH1A1 (0.62) | LOXL2TAAR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL21812776 | 0.62 | RAB9A (0.66) | LOXL2TAAR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL16217968 | 0.62 | RAB9A (0.65) | LOXL2TAAR1ALDH1A1RAB9AMEN1 | |
| SCHEMBL16217967 | 0.62 | ALDH1A1 (0.65) | LOXL2TAAR1ALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009334-A1 | METHOD FOR PREPARING LARGAZOLE ANALOGS AND USES THEREOF | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2010-01-21 | — | — | WO | disclosed |