Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 17/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29651977 | 0.98 | HCAR3 (0.57) | HCAR3GRIN2BHCAR2BCL2HDAC1 | |
| SCHEMBL2877186 | 0.98 | HCAR3 (0.57) | HCAR3GRIN2BHCAR2BCL2HDAC1 | |
| SCHEMBL5543076 | 0.87 | BCL2 (0.52) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL28658285 | 0.87 | GRIN2B (0.48) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL31727242 | 0.87 | GRIN2B (0.48) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL2772417 | 0.85 | MAPK1 (0.51) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL5734042 | 0.85 | NNMT (0.58) | GRIN2BBCL2HDAC1 | |
| SCHEMBL31599569 | 0.84 | GRIN2B (0.47) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL20828520 | 0.84 | GRIN2B (0.47) | HCAR3GRIN2BBCL2HDAC1 | |
| SCHEMBL2058148 | 0.84 | HCAR3 (0.54) | HCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017992-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2001-03-15 | — | — | WO | disclosed |