Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532874 | 0.92 | CYP2A6 (0.34) | HPRT1LMNAMAPK1MAPTPAX8 | |
| SCHEMBL7629651 | 0.89 | HPRT1 (0.45) | HPRT1LMNAMAPK1MAPTCYP3A4 | |
| SCHEMBL20972468 | 0.82 | CYP2A6 (0.33) | HPRT1LMNAMAPK1MAPTPAX8 | |
| SCHEMBL8468654 | 0.80 | ALDH1A1 (0.37) | HPRT1LMNAMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL7036593 | 0.74 | — | — | |
| SCHEMBL10877850 | 0.74 | HPRT1 (0.45) | HPRT1LMNAMAPK1MAPTCYP3A4 | |
| SCHEMBL29767587 | 0.71 | MAPT (0.35) | MAPK1MAPTALDH1A1HSD17B10TDP1 | |
| SCHEMBL20972428 | 0.71 | MAPT (0.35) | MAPK1MAPTALDH1A1HSD17B10TDP1 | |
| SCHEMBL7936856 | 0.70 | HPRT1 (0.40) | HPRT1LMNAMAPK1MAPTCYP3A4 | |
| SCHEMBL7036431 | 0.69 | MAPT (0.37) | MAPK1MAPTALDH1A1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329486-B1 | PHYSICAL PROPERTIES | THE DOW CHEMICAL COMPANY | 2001-12-11 | — | — | US | disclosed |
| US-6323294-B1 | CONTACTING C.SUB.2-100,000 OLEFIN/S UNDER POLYMERIZATION CONDITIONS WITH CATALYST SYSTEM COMPRISING METAL COMPLEX AND ACTIVATING COCATALYST OR REACTION PRODUCT OF METAL COMPLEX AND COCATALYST TO FORM ADDITION POLYMER | THE DOW CHEMICAL COMPANY | 2001-11-27 | — | — | US | disclosed |