Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbon Monoxide SCHEMBL11153145 | 0.94 | ALDH1A1 (0.38) | ALDH1A1TSHRNAPRTHSD17B10HPGD | |
| SCHEMBL9364505 | 0.78 | NPSR1 (0.46) | ALDH1A1TSHRNPSR1KDM4EFFAR1 | |
| Diphenylacetylene SCHEMBL27967498 | 0.71 | APP (0.52) | ALDH1A1NPSR1KDM4EMAPTFFAR1 | |
| SCHEMBL6562696 | 0.70 | NPSR1 (0.42) | ALDH1A1HPGDNPSR1KDM4EMAPT | |
| SCHEMBL9512109 | 0.70 | PTGS2 (0.50) | ALDH1A1TSHRNAPRTHSD17B10HPGD | |
| Phenylacetylene SCHEMBL27873653 | 0.70 | TSHR (0.43) | ALDH1A1TSHRNAPRTHSD17B10KDM4E | |
| Benzonitrile SCHEMBL7039263 | 0.70 | TSHR (0.58) | ALDH1A1TSHRKDM4EMAPTSMN1; SMN2 | |
| SCHEMBL5677996 | 0.69 | NAPRT (0.46) | TSHRNAPRTHSD17B10NPSR1CES2 | |
| SCHEMBL11593482 | 0.68 | TDP1 (0.44) | ALDH1A1TSHRNAPRTHSD17B10HPGD | |
| SCHEMBL9456497 | 0.68 | ALDH1A1 (0.52) | ALDH1A1TSHRNAPRTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6278019-B1 | REACTING ALKYL GROUP SUBSTITUTED AROMATIC COMPOUND AND A CARBOXYLIC ACID AND/OR A CARBOXYLIC ANHYDRIDE IN PRESENCE OF OXYGEN CONTAINING GAS AND SOLID CATALYST SELECTED FROM COABLT, CERIUM AND MANGANESE SUPPORTED ON SOLID SUPPORT | TORAY INDUSTRIES, INC. (JP) | 2001-08-21 | — | — | US | disclosed |
| US-6166074-A | Pharmaceutical compositions | NORSK HYDRO A.S. (NO) | 2000-12-26 | — | — | US | disclosed |
| EP-0963974-A1 | PROCESS FOR ACYLOXYLATING SIDE CHAINS OF ALKYL-SUBSTITUTED AROMATIC COMPOUNDS AND CATALYSTS USED THEREFOR | TORAY INDUSTRIES, INC. (JP) | 1999-12-15 | — | — | EP | disclosed |
| EP-0738145-A1 | PHARMACEUTICAL COMPOSITIONS | NORSK HYDRO a.s. (NO) | 1996-10-23 | — | — | EP | disclosed |
| WO-1995018607-A1 | PHARMACEUTICAL COMPOSITIONS | NORSK HYDRO A.S (NO) | 1995-07-13 | — | — | WO | disclosed |
| EP-0015436-B1 | PROCESS FOR THE STEREOSPECIFIC PREPARATION OF COMPOUNDS OF THE VITAMIN K1- AND K2-SERIES, AS WELL AS NEW STARTING MATERIALS FOR THE PROCESS | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-02-03 | — | — | EP | disclosed |
| EP-0015436-A1 | Process for the stereospecific preparation of compounds of the vitamin K1- and K2-series, as well as new starting materials for the process | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-09-17 | — | — | EP | disclosed |