Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21925720 | 0.81 | SMN1; SMN2 (0.38) | HTR2AHTR2CSMN1; SMN2TP53CCR2 | |
| SCHEMBL2029777 | 0.76 | MAPT (0.41) | SMN1; SMN2TP53CCR2THRBMAPT | |
| SCHEMBL23795261 | 0.76 | SMN1; SMN2 (0.37) | SMN1; SMN2TP53CCR2THRBMAPT | |
| SCHEMBL7996188 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL20553759 | 0.75 | TAAR1 (0.33) | KDM1A | |
| SCHEMBL9566016 | 0.75 | — | — | |
| SCHEMBL20553996 | 0.75 | TP53 (0.37) | SMN1; SMN2TP53CCR2SLC6A4SLC6A3 | |
| SCHEMBL728580 | 0.75 | ALDH1A1 (0.38) | — | |
| SCHEMBL140434 | 0.75 | FSHR (0.42) | SMN1; SMN2MAPTKMT2A | |
| SCHEMBL29374824 | 0.75 | FSHR (0.42) | SMN1; SMN2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3621946-B1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2023-09-06 | — | — | EP | disclosed |
| US-11495746-B2 | Indane derivatives and their use in organic electronics | DOTTIKON ES HOLDING AG (CH) | 2022-11-08 | — | — | US | disclosed |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-03-05 | — | — | US | disclosed |
| CN-110740986-A | Indane derivatives and their use in organic electronic devices | 多蒂肯独家合成控股公司 | 2020-01-31 | — | — | CN | disclosed |
| EP-3401305-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2018-11-14 | — | — | EP | disclosed |
| EP-0923513-B1 | PREPARATION OF BROMINATED INDANES | ALBEMARLE CORP (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-0995733-A1 | Improved process for the preparation of TMPI derivatives | Bromine Compounds Ltd. (IL) | 2000-04-26 | — | — | EP | disclosed |
| EP-0923513-A1 | PREPARATION OF BROMINATED INDANES | ALBEMARLE CORPORATION (US) | 1999-06-23 | — | — | EP | disclosed |
| EP-0863118-A1 | Preparation of Brominated Indanes | ALBEMARLE CORPORATION (US) | 1998-09-09 | — | — | EP | disclosed |
| WO-1998008788-A1 | PREPARATION OF BROMINATED INDANES | ALBEMARLE CORPORATION (US) | 1998-03-05 | — | — | WO | disclosed |
| US-5710354-A | Preparation of brominated indanes | ALBEMARLE CORPORATION (US) | 1998-01-20 | — | — | US | disclosed |
| US-5679736-A | POLYBROMINATED 1,1,3-TRIMETHYL-3-PHENYLINDAN AND-OR POLYBROMINATED 1-METHYL-3-PHENYLINDAN | BROMINE COMPOUNDS LIMITED (IL) | 1997-10-21 | — | — | US | disclosed |
| EP-0571036-B1 | Polyhalogenated phenylindans, process for their preparation and fire retardant polymeric compositions containing them | BROMINE COMPOUNDS LTD (IL) | 1997-01-15 | — | — | EP | disclosed |
| EP-0571036-A1 | Polyhalogenated phenylindans, process for their preparation and fire retardant polymeric compositions containing them | Bromine Compounds Ltd. (IL) | 1993-11-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11495746-B2 | Indane derivatives and their use in organic electronics | KCNJ2, KCNA2, CYP2J2 | HTR2A 235/4885HTR2C 218/4885SMN1; SMN2 2607/4885 |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | KCNJ2, KCNA2, CYP2J2 | HTR2A 235/4885HTR2C 218/4885SMN1; SMN2 2607/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.