Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 3/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.30 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676560 | 0.76 | ALDH1A1 (0.40) | ALDH1A1GAATLR8HTR2CMAPT | |
| SCHEMBL7159087 | 0.73 | ALDH1A1 (0.40) | ALDH1A1GAATLR8HTR2CMAPT | |
| SCHEMBL6157353 | 0.72 | ALDH1A1 (0.46) | ALDH1A1GAATLR8HTR2CSCN4A | |
| SCHEMBL285513 | 0.72 | TSHR (0.38) | ALDH1A1GAAMAPTLMNATSHR | |
| SCHEMBL7274535 | 0.69 | ALDH1A1 (0.36) | ALDH1A1GAATLR8MAPTHIF1A | |
| SCHEMBL7832236 | 0.69 | TLR8 (0.38) | ALDH1A1GAATLR8HTR2CLMNA | |
| SCHEMBL4630223 | 0.69 | ELANE (0.39) | ALDH1A1TLR8HTR2CLMNACYP1A2 | |
| SCHEMBL676305 | 0.68 | ALDH1A1 (0.46) | ALDH1A1GAATLR8HTR2CMAPT | |
| SCHEMBL5027519 | 0.68 | ALDH1A1 (0.46) | ALDH1A1GAATLR8HTR2CMAPT | |
| SCHEMBL1046485 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242449-B1 | TREATING PROSTATIC HYPERTROPHY, URINATION DISORDERS ASSOCIATED WITH PROSTATIC HYPERTROPHY, MALE PATTERN ALOPECIA, OR ACNE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| EP-0997457-A1 | 3-BENZOYLINDOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |