Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321984 | 0.84 | ALDH1A1 (0.37) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9672140 | 0.81 | TSHR (0.41) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9672147 | 0.81 | PTPN1 (0.39) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9671351 | 0.81 | KDM4E (0.35) | KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL10345470 | 0.81 | NCOA1 (0.36) | TSHRALDH1A1KDM4ENQO1MAPT | |
| SCHEMBL4532108 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1KDM4ENQO1L3MBTL1 | |
| SCHEMBL9674008 | 0.79 | TYMS (0.38) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9674003 | 0.79 | TSHR (0.40) | TSHRALDH1A1KDM4EL3MBTL1HPGD | |
| SCHEMBL9672082 | 0.78 | TSHR (0.37) | TSHRALDH1A1KDM4ENQO1L3MBTL1 | |
| SCHEMBL10667354 | 0.78 | L3MBTL1 (0.37) | TSHRALDH1A1KDM4ENQO1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117831652-A | Prediction method of olefin hydroformylation positive-to-negative ratio | 上海华谊控股集团有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-11155654-B2 | Heterogenous precatalyst for preparation of highly crystalline, disentangled, ultra high molecular weight polyethylene (UHMWPE) and a process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-10-26 | — | — | US | claimed |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2021-05-13 | — | — | US | claimed |
| EP-3038621-B1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | HUMAN BIOMOLECULAR RES INSTITUTE (US) | 2020-12-02 | — | — | EP | claimed |
| US-20200277415-A1 | A HETROGENOUS PRECATALYST FOR PREPARATION OF HIGHLY CRYSTALLINE, DISENTANGLED, ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE (UHMWPE) AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2020-09-03 | — | — | US | claimed |
| EP-3692080-A1 | A HETROGENOUS PRECATALYST FOR PREPARATION OF HIGHLY CRYSTALLINE, DISENTANGLED, ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE (UHMWPE) AND A PROCESS FOR PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2020-08-12 | — | — | EP | claimed |
| WO-2019069328-A1 | A HETROGENOUS PRECATALYST FOR PREPARATION OF HIGHLY CRYSTALLINE, DISENTANGLED, ULTRA HIGH MOLECULAR WEIGHT POLYETHYLENE (UHMWPE) AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-04-11 | — | — | WO | claimed |
| US-9862691-B2 | Cyclic triazo and diazo sodium channel blockers | UNIVERSITY OF GREENWICH (GB) | 2018-01-09 | — | — | US | claimed |
| US-20160311784-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | UNIVERSITY OF GREENWICH (GB) | 2016-10-27 | — | — | US | claimed |
| EP-3038621-A2 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | Human Biomolecular Research Institute (US) | 2016-07-06 | — | — | EP | claimed |
| EP-1212331-B1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | claimed |
| US-6649595-B2 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD GENE THERAPEUTICS, INC. | 2003-11-18 | — | — | US | claimed |
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | ARIAD PHARMACEUTICALS, INC. | 2002-08-08 | — | — | US | claimed |
| EP-1212331-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2002-06-12 | — | — | EP | claimed |
| JP-2002508971-A | — | — | 2002-03-26 | — | — | JP | claimed |
| WO-2001014387-A1 | 28-EPIRAPALOGS | ARIAD GENE THERAPEUTICS, INC. (US) | 2001-03-01 | — | — | WO | claimed |
| US-6187757-B1 | Regulation of biological events using novel compounds | ARIAD PHARMACEUTICALS, INC. | 2001-02-13 | — | — | US | claimed |
| EP-1045915-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 2000-10-25 | — | — | EP | claimed |
| WO-1999036553-A2 | REGULATION OF BIOLOGICAL EVENTS USING MULTIMERIC CHIMERIC PROTEINS | ARIAD GENE THERAPEUTICS, INC. (US) | 1999-07-22 | — | — | WO | claimed |
| WO-1998034112-A1 | COMBINATORIAL LIBRARIES OF IMIDAZOL-PYRIDO-INDOLES AND IMIDAZOL-PYRIDO-BENZOTHIOPHENE DERIVATIVES | TREGA BIOSCIENCES, INC. (US) | 1998-08-06 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107189-A1 | FK506 binding proteins (FKBPs); rapamysin derivatives; multimerizing chimeric proteins in genetically engineered cells using said derivatives | FKBP2, FKBP14, FKBP4 | TSHR 3821/4885ALDH1A1 4699/4885KDM4E 1883/4885 |
| US-20210138117-A1 | COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR | BMP2, BMP4, BMP6 | TSHR 2887/4885ALDH1A1 1413/4885KDM4E 3576/4885 |
| US-20160311784-A1 | CYCLIC TRIAZO AND DIAZO SODIUM CHANNEL BLOCKERS | SCN1A, SCN1B, SCN3A | TSHR 309/4885ALDH1A1 1729/4885KDM4E 4452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.