Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 2/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | YTHDF2 | Q9Y5A9 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.31 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7937484 | 0.90 | SLC29A1 (0.39) | MAP4K4KDM4EFFAR2SLC29A1KHK | |
| SCHEMBL16094713 | 0.87 | SLC29A1 (0.42) | EGFRSLC29A1KHKBCHEACHE | |
| Hydrochloric Acid SCHEMBL16094548 | 0.86 | SLC29A1 (0.41) | EGFRSLC29A1KHKBCHEACHE | |
| SCHEMBL7942601 | 0.80 | YTHDC1 (0.46) | MAP4K4KDM4EEGFRYTHDC1YTHDF2 | |
| SCHEMBL7930938 | 0.78 | LMNA (0.41) | MAP4K4KDM4EFFAR2PGK1ADORA3 | |
| SCHEMBL7937472 | 0.77 | SLC29A1 (0.51) | SLC29A1KHKBCHEACHECCNB2 | |
| SCHEMBL16094412 | 0.74 | SLC29A1 (0.42) | SLC29A1YTHDC1YTHDF2KHKBCHE | |
| SCHEMBL18806440 | 0.73 | LMNA (0.50) | SLC29A1BCHEACHEFLT3PRKCD | |
| SCHEMBL20164633 | 0.72 | SLC29A1 (0.58) | KDM4ESLC29A1CCNB2CDK1CCNB1 | |
| Hydrochloric Acid SCHEMBL20164454 | 0.71 | SLC29A1 (0.56) | SLC29A1CCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232312-B1 | ADMINISTERING A COMBINATION OF INDENE AND PYRIMIDO(5,4-D)PYRIMIDINE DERIVATIVES TO TREAT PREPANCREATIC CANCER | CELL PATHWAYS, INC. | 2001-05-15 | — | — | US | disclosed |